约克大学PhD position in Understanding the role of piRNAs in mosquito immunity申请条件要求-申请方
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约克大学
PhD直招介绍
About the Project
Vector-borne diseases afflict humans, livestock and plants – according to WHO, vector-borne diseases comprise ~17% of all infectious disease of humans – and also threaten biodiversity by their impact on endangered species. Mosquitoes are a major vector group, and mosquito-borne viruses such as dengue, Zika, chikungunya and West Nile viruses significantly impact humans, birds and other species, yet mosquito-virus interactions remain under-investigated. This project focuses on analysing one aspect of the mosquito’s response to infection, and manipulating that to prevent transmission of such viruses.
Infection is known to lead the production of small RNAs that affect the virus replication. The best-known are siRNAs produced by the Dicer pathway. However, piRNAs (piwi-interacting RNAs) are also produced; these slightly longer RNAs (ca26-30nt rather than 20-24nt) are found in all animals. They are known to suppress transposons in Drosophila, but poorly understood in mosquitoes. However, several lines of evidence suggest a role in immunity - they are produced following infection, and manipulating the piwi pathway affects virus replication. This project aims to investigate further by specific expression of piRNAs and piRNA precursors in the key vector mosquito Aedes aegypti, assessing effects on infection, virus replication and vector competence.
The Alphey lab is a world leader in mosquito synthetic biology and exceptionally well able to support and supervise this project in every respect - technical and subject expertise, funding, equipment and facilities, etc. This project aims to understand fundamental aspects of mosquito-virus interaction, but with a clear applied/translation goal if, for example, targeted manipulation of the pathway can reduce the ability of mosquitoes to transmit one or several relevant viruses. Since the piRNA pathway is conserved across animals, project outcomes will likely be relevant to other species well beyond mosquitoes and mosquito-borne disease.
https://www.whiterose-mechanisticbiology-dtp.ac.uk/yorkshire-bioscience-dtp/
约克大学 PhD position in Understanding the role of piRNAs in mosquito immunity项目有没有奖学金，是不是全奖Phd招生，下面我们一起看一下【大学名称】Phd的奖学金资助情况
项目资助情况
A tax-free annual stipend at the standard UKRI rate (£19,237 for 2024/25 entry), research costs and tuition fees at UK rate
The studentships are fully funded for four years and you must complete your PhD in four years.
You’ll receive the UKRI minimum doctoral stipend per year for your living costs, which is paid to you in regular instalments. The UK Research and Innovation( https://www.ukri.org/our-work/developing-people-and-skills/find-studentships-and-doctoral-training/get-a-studentship-to-fund-your-doctorate/ ) (UKRI) stipend is tax free and does not need to be paid back.
费用
International students will need to have sufficient funds to cover the costs of their student visa( https://www.gov.uk/student-visa ), NHS health surcharge( https://www.gov.uk/healthcare-immigration-application/how-much-pay ), travel insurance and travel to the UK as these are excluded from UKRI funding.
约克大学Phd申请条件和要求都有哪些？PhD position in Understanding the role of piRNAs in mosquito immunity项目是不是全奖？有没有奖学金？下面我们一起看一下约克大学申请Phd直招需要具备哪些条件和要求，以及托福、雅思语言成绩要到多少才能申请。
申请要求
Open to International (including EU) and UK (home) students.
You can apply if you have, or are expecting to gain, at least an upper second class honours degree or equivalent. Due to the interdisciplinary nature of this programme we welcome applications if your background is in any biological, chemical or physical science or mathematics and are interested in using your skills in addressing biological questions. International students should check if they meet the entry requirements for their country.
We aim to support the most outstanding applicants from outside the UK and are able to offer a limited number of bursaries that will enable full studentships to be awarded to international (EU and non-EU) applicants. These full studentships will only be awarded to exceptional quality candidates, due to the competitive nature of this scheme.
The Yorkshire Bioscience DTP is committed to recruiting extraordinary future scientists regardless of age, ethnicity, gender, gender identity, disability, sexual orientation or career pathway to date. We understand that commitment and excellence can be shown in many ways and have built our recruitment process to reflect this. We welcome applicants from all backgrounds, particularly those underrepresented in science, who have curiosity, creativity and a drive to learn new skills.
Not all projects will be funded; a limited number of candidates will be appointed via a competitive process.
English language: If English isn’t your first language, you may need to provide evidence of your English language ability.
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邮箱：wrdtp@leeds.ac.uk
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