纽卡斯尔大学PhD studentship: Staphylococcus aureus interactions in cystic fibrosis polymicrobial infections申请条件要求-申请方
主办方
纽卡斯尔大学
PhD直招介绍
About the Project
Overview
Cystic fibrosis (CF) is a genetic condition affecting 1 in 2500 babies in the UK. Disruption in chloride secretion results in build-up of thick mucus in the lungs, trapping bacteria and promoting their growth. Staphylococcus aureus (Sa) is one of the earliest infections in the lungs of children with CF. Sa persists for many years in the CF lung environment.
Sa uses the type VII secretion system (T7SS) to secrete antibacterial toxins that target competitor bacteria. The T7SS and its toxins are strongly linked with colonisation. We hypothesise that the CF lung environment, and co-infecting bacteria, modulate activity of the Sa T7SS.
You will engineer GFP promoter fusions to assess T7SS ‘switching on’ in response to the CF environment, clinically relevant antibiotics and presence of other bacteria. You will assess ability of Sa wild type, T7SS mutants and secreted toxin mutants to form biofilms with other CF pathogens, in particular Pseudomonas aeruginosa (Pa), looking at spatial localisation and survival in the biofilm. You will determine how Sa interacts with airway commensals and whether/how they modulate Sa/Pa interactions.
Number of awards
1
Start date
15th September 2025
Award duration
The funding covers a three-year PhD
Sponsor
LifeArc/CF Trust
Name of supervisor/s
Professor Tracy Palmer
纽卡斯尔大学 PhD studentship: Staphylococcus aureus interactions in cystic fibrosis polymicrobial infections项目有没有奖学金，是不是全奖Phd招生，下面我们一起看一下【大学名称】Phd的奖学金资助情况
项目资助情况
100% of home tuition fees paid and annual stipend (living expenses) of £19,237. International candidates will be required to fund the difference between home fees and international fees.
纽卡斯尔大学Phd申请条件和要求都有哪些？PhD studentship: Staphylococcus aureus interactions in cystic fibrosis polymicrobial infections项目是不是全奖？有没有奖学金？下面我们一起看一下纽卡斯尔大学申请Phd直招需要具备哪些条件和要求，以及托福、雅思语言成绩要到多少才能申请。
申请要求
You must have, or expect to achieve, at least a 2:1 honours degree or international equivalent, in a subject relating to biomedical sciences, including biochemistry/microbiology. Further qualification such as an MRes is advantageous.
This award is available to home and international applicants. Successful international candidates will be required to make up the difference between home fees and international fees.
Successful EU applicants will be considered for the Vice-Chancellor’s EU Research Scholarship
English Language requirements: IELTS 6.5 overall, with 5.5 or more in each sub-skill.
报名方式
申请链接
招生人信息
Prof T Palmer
邮箱：Tracy.Palmer@newcastle.ac.uk
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