因斯布鲁克大学PhD position: Calcium channels in congenital stationary night blindness申请条件要求-申请方
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因斯布鲁克大学
PhD直招介绍
About the Project
Photoreceptors are morphologically and physiological highly specialized light sensing cells of the retina where sustained release of glutamate from ribbon synapses is calcium dependent and L-type calcium channels (LTCC) serve as the predominant source for Ca2+ entry. Mutations in the gene encoding Cav1.4 LTCCs were identified among patients diagnosed with congenital night blindness type 2 (OMIM: 30071). The aim of this PhD project is to test the pharmaco-therapeutic potential of retinal Cav1.4 LTCCs using gene therapy.
Methods: Immunohistochemical analyses of mutant and transduced retinas; viral and non-viral gene-therapy applied by retinal injections.
References: Singh et al. (2006) Nature Neuroscience; Burtscher et al. (2014) Biochim Biophys Acta; Pangrsic et al. (2018) Physiol Reviews (Review); Zanetti et al. (2021) Scientific Reports; Nguyen et al. (2022) Appl Mater Interfaces; Heigl et al. (2023) Channels.
We offer an international research environment, state-of-the art immunohistochemical, electrophysiological and molecular biological techniques. The project work will make use of well-established techniques in our lab, including molecular biology, immunohistochemistry, viral vectors, cell culture and transfections.
因斯布鲁克大学 PhD position: Calcium channels in congenital stationary night blindness项目有没有奖学金，是不是全奖Phd招生，下面我们一起看一下【大学名称】Phd的奖学金资助情况
项目资助情况
Salary: According to the rates of the Austrian Science Fund( https://www.fwf.ac.at/foerdern/schritte-zur-erfolgreichen-foerderung/weitere-informationen/personalkosten ) (FWF) for PhD students plus travel funds for international scientific meetings.
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招生人信息
Assoc Prof A. Koschak
邮箱：alexandra.koschak@uibk.ac.at
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